To Open Visual Studio with a Specific AX Configuration from a Shortcut
1. From the Start menu, right-click Visual Studio short cut, and select Properties.
2. Update the Target field and add the /AxConfig switch parameter with either the name of the client configuration (which is configured in Client configuration utility) or the name of the client configuration file as shown in the following examples from the local/server path:
"C:\Program Files (x86)\Microsoft Visual Studio 12.0\Common7\IDE\devenv.exe" /AxConfig AX_DEV[initial]-USR.axc
OR
"C:\Program Files (x86)\Microsoft Visual Studio 12.0\Common7\IDE\devenv.exe" /AxConfig \\test01\axconfig$\AX_DEV[initial]-USR.axc
3. Save the parameters. And start VS, when you click the Visual Studio short cut, it opens and Application Explorer points to the specified client configuration. The name of the configuration appears at the top in the root node of Application Explorer.

For detail information find https://msdn.microsoft.com/en-us/library/gg889291.aspx.
Hope this helps.
Regards,
1. From the Start menu, right-click Visual Studio short cut, and select Properties.
2. Update the Target field and add the /AxConfig switch parameter with either the name of the client configuration (which is configured in Client configuration utility) or the name of the client configuration file as shown in the following examples from the local/server path:
"C:\Program Files (x86)\Microsoft Visual Studio 12.0\Common7\IDE\devenv.exe" /AxConfig AX_DEV[initial]-USR.axc
OR
"C:\Program Files (x86)\Microsoft Visual Studio 12.0\Common7\IDE\devenv.exe" /AxConfig \\test01\axconfig$\AX_DEV[initial]-USR.axc

For detail information find https://msdn.microsoft.com/en-us/library/gg889291.aspx.
Hope this helps.
Regards,